Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429161 | 0.90 | MAPT (0.53) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7477992 | 0.84 | RAB9A (0.55) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7479875 | 0.79 | ITGB3 (0.45) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7419341 | 0.76 | KIT (0.49) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7580016 | 0.76 | USP2 (0.45) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL532678 | 0.76 | MAPT (0.74) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7477926 | 0.74 | MAPT (0.50) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL24891825 | 0.74 | RAB9A (0.64) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7484366 | 0.74 | MAPKAPK2 (0.45) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7473771 | 0.74 | ITGB3 (0.49) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885205-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0885205-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997031910-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-09-04 | — | — | WO | disclosed |