Flazasulfuron

Flazasulfuron

SCHEMBL7580038

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(F)(F)F)n1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
GAA P10253 2/20 0.38
PPARG P37231 1/20 0.37
JMJD7 P0C870 1/20 0.36
TBXA2R P21731 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
SCN9A Q15858 1/20 0.33
RBP4 P02753 1/20 0.33
MAPK8 P45983 1/20 0.33
MAPK10 P53779 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flazasulfuron SCHEMBL7584684 0.91 TDP1 (0.45) TDP1MEN1KMT2ATTRPPOX
Flazasulfuron SCHEMBL7585892 0.89 TDP1 (0.56) TDP1MEN1KMT2ATTRPPOX
Nicosulfuron SCHEMBL7582294 0.89 TDP1 (0.54) TDP1MEN1KMT2ATTRPPOX
Rimsulfuron SCHEMBL7581824 0.89 TDP1 (0.54) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL7585716 0.88 TDP1 (0.47) TDP1MEN1KMT2ATTRPPOX
Flupyrsulfuron SCHEMBL7580925 0.86 TDP1 (0.55) TDP1MEN1KMT2ATTRPPOX
Flazasulfuron SCHEMBL7578877 0.86 MEN1 (0.43) TDP1MEN1KMT2ATTRPPOX
Lactofen SCHEMBL7578627 0.85 MEN1 (0.42) TDP1MEN1KMT2ATTRPPOX
Flazasulfuron SCHEMBL7585112 0.85 MEN1 (0.42) TDP1MEN1KMT2ATTRPPOX
Flupyrsulfuron SCHEMBL7584020 0.83 TDP1 (0.43) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.