Flupyrsulfuron

Flupyrsulfuron

SCHEMBL7580925

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2nc(C(F)(F)F)ccc2C(=O)O)n1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
MEN1 O00255 1/20 0.46
TTR P02766 1/20 0.46
PPOX P50336 1/20 0.46
KMT2A Q03164 1/20 0.46
GAA P10253 3/20 0.40
TBXA2R P21731 4/20 0.36
MCL1 Q07820 1/20 0.35
CDK1 P06493 1/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 2/20 0.34
ALDH1A1 P00352 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
FLT1 P17948 2/20 0.34
FLT4 P35916 2/20 0.34
KDR P35968 2/20 0.34
PYGL P06737 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flupyrsulfuron SCHEMBL7581127 0.91 TDP1 (0.59) TDP1MEN1TTRPPOXKMT2A
Flupyrsulfuron SCHEMBL7584020 0.89 TDP1 (0.43) TDP1MEN1TTRPPOXKMT2A
Flupyrsulfuron SCHEMBL7582434 0.87 TDP1 (0.52) TDP1MEN1TTRPPOXKMT2A
Flazasulfuron SCHEMBL7580038 0.86 TDP1 (0.54) TDP1MEN1TTRPPOXKMT2A
Flupyrsulfuron SCHEMBL7576436 0.86 KMT2A (0.48) TDP1MEN1TTRPPOXKMT2A
Flupyrsulfuron SCHEMBL7578681 0.85 MEN1 (0.49) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7579263 0.85 KMT2A (0.47) TDP1MEN1TTRPPOXKMT2A
Bifenox SCHEMBL7597188 0.84 TDP1 (0.62) TDP1MEN1TTRPPOXKMT2A
Bifenox SCHEMBL7577737 0.84 TDP1 (0.55) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7582294 0.83 TDP1 (0.54) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.