Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 6/20 | 0.59 |
| ▸ | PKLR | P30613 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.56 |
| ▸ | CCR2 | P41597 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571637 | 0.89 | ALDH1A1 (0.62) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL1250772 | 0.89 | VCAM1 (0.62) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL1251538 | 0.89 | FFAR4 (0.66) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL96167 | 0.87 | ALDH1A1 (0.70) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL5227535 | 0.86 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAPOLBPKM | |
| SCHEMBL6831222 | 0.85 | ALDH1A1 (0.74) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL7573014 | 0.85 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL6570574 | 0.84 | ALDH1A1 (0.72) | ALDH1A1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL23093470 | 0.84 | PKM (0.62) | ALDH1A1GAASMN1; SMN2PKMPKLR | |
| SCHEMBL7573187 | 0.83 | ALDH1A1 (0.66) | ALDH1A1GAASMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |