Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 6/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 6/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102992 | 0.87 | KDM4E (0.48) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL7011365 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL7101772 | 0.82 | ABCC9 (0.49) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL7100408 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL7099480 | 0.79 | ABCC9 (0.52) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL7583051 | 0.79 | ABCC9 (0.52) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL5078130 | 0.77 | ABCC9 (0.61) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7098825 | 0.76 | ABCC9 (0.66) | ALDH1A1KDM4EABCC9ABCC8KCNJ11 | |
| SCHEMBL7101783 | 0.74 | ABCC9 (0.48) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL7575205 | 0.71 | ABCC9 (0.42) | ALDH1A1KDM4EGAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099070-A1 | Dihydronaphthyridine potassium channel openers | ABBOTT LABORATORIES | 2002-07-25 | — | — | US | claimed |
| US-20020099070-A1 | Dihydronaphthyridine potassium channel openers | ABBOTT LABORATORIES | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099070-A1 | Dihydronaphthyridine potassium channel openers | KCNH1, KCNN1, KCNJ2 | ALDH1A1 555/4885KDM4E 1292/4885GAA 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.