Primisulfuron

Primisulfuron

SCHEMBL7580908

COc1c(Cl)ccc(Cl)c1C(=O)O.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(Nc1nc(OC(F)F)cc(OC(F)F)n1)NS(=O)(=O)c1ccccc1C(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.34
TTR P02766 1/20 0.34
PPOX P50336 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
THRB P10828 1/20 0.33
ACLY P53396 1/20 0.32
FFAR1 O14842 1/20 0.32
SCN9A Q15858 1/20 0.31
PYGL P06737 1/20 0.31
PYGM P11217 1/20 0.31
CCR1 P32246 1/20 0.30
CCR2 P41597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7578606 0.94 MEN1 (0.38) LMNAKDM4EGAAMAPTHPGD
Primisulfuron SCHEMBL7581863 0.93 KDM4E (0.32) LMNAKDM4EGAAMAPTHPGD
Primisulfuron SCHEMBL7578566 0.93 KDM4E (0.31) LMNAKDM4EGAAMAPTHPGD
Primisulfuron SCHEMBL7579295 0.91 KDM4E (0.30) LMNAKDM4EGAAMAPTHPGD
Lactofen SCHEMBL7585121 0.88 TDP1 (0.42) LMNAKDM4EGAAMAPTHPGD
Primisulfuron SCHEMBL7578943 0.88 TDP1 (0.50) LMNAMAPTMEN1TTRPPOX
Primisulfuron SCHEMBL7581367 0.87 MEN1 (0.32) LMNAKDM4EGAAMAPTHPGD
Primisulfuron SCHEMBL7577599 0.87 MEN1 (0.33) MEN1TTRPPOXKMT2ATDP1
Primisulfuron SCHEMBL7576089 0.87 CDK1 (0.35) LMNAKDM4EGAAMAPTHPGD
Primisulfuron SCHEMBL7580873 0.86 MEN1 (0.33) MEN1TTRPPOXKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT LMNA 3881/4885KDM4E 1886/4885GAA 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.