Primisulfuron

Primisulfuron

SCHEMBL7581863

COc1c(Cl)ccc(Cl)c1C(=O)O.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(Nc1nc(OC(F)F)cc(OC(F)F)n1)NS(=O)(=O)c1ccccc1C(=O)O.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 1/20 0.30
TTR P02766 1/20 0.30
PPOX P50336 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7577599 0.95 MEN1 (0.33) MEN1TTRPPOXKMT2ATDP1
Primisulfuron SCHEMBL7579295 0.95 KDM4E (0.30) KDM4ELMNAGAAMAPTHPGD
Primisulfuron SCHEMBL7580908 0.93 LMNA (0.36) KDM4ELMNAGAAMAPTHPGD
Lactofen SCHEMBL7586789 0.90 MEN1 (0.37) MEN1TTRPPOXKMT2ATDP1
Primisulfuron SCHEMBL7578566 0.90 KDM4E (0.31) KDM4ELMNAGAAMAPTHPGD
Primisulfuron SCHEMBL7587653 0.90 TDP1 (0.43) LMNAMAPTMEN1TTRPPOX
Primisulfuron SCHEMBL7590093 0.90 MEN1 (0.33) MEN1TTRPPOXKMT2ATDP1
Primisulfuron SCHEMBL7578481 0.89
Primisulfuron SCHEMBL7577262 0.88 CDK1 (0.32)
Primisulfuron SCHEMBL7582588 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KDM4E 1886/4885LMNA 3881/4885GAA 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.