Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571235 | 0.79 | GRIN1 (0.44) | MAPTSMN1; SMN2KMT2AATMCA12 | |
| SCHEMBL7580866 | 0.78 | GRIN2D (0.44) | SMN1; SMN2CA2NPC1RAB9AGAA | |
| SCHEMBL7581822 | 0.78 | ALDH1A1 (0.41) | MAPTSMN1; SMN2KMT2ACA12CA2 | |
| SCHEMBL7575590 | 0.75 | GRIN2D (0.46) | MAPTKMT2AKDM4ENPC1RAB9A | |
| SCHEMBL7575582 | 0.75 | GRIN2D (0.46) | MAPTKMT2AKDM4ENPC1RAB9A | |
| SCHEMBL22925045 | 0.75 | KMT2A (0.44) | MAPTSMN1; SMN2KMT2AATMCA12 | |
| SCHEMBL7575480 | 0.74 | CA12 (0.47) | MAPTSMN1; SMN2KMT2ACA12CA2 | |
| SCHEMBL13107935 | 0.72 | LMNA (0.46) | MAPTSMN1; SMN2KMT2ACA12CA2 | |
| SCHEMBL3444466 | 0.72 | LMNA (0.46) | MAPTSMN1; SMN2KMT2ACA12CA2 | |
| SCHEMBL3444467 | 0.72 | LMNA (0.46) | MAPTSMN1; SMN2KMT2ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |