Oxyfluorfen

Oxyfluorfen

SCHEMBL7581235

CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COCC(C)N(C(=O)CCl)c1c(C)csc1C

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.51
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
TTR P02766 1/20 0.45
PPOX P50336 1/20 0.45
LMNA P02545 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
FFAR1 O14842 2/20 0.35
PPARD Q03181 3/20 0.34
PPARG P37231 2/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7582027 0.91 TDP1 (0.59) THRBMEN1KMT2ATDP1TTR
Oxyfluorfen SCHEMBL7580281 0.88 MEN1 (0.45) THRBMEN1KMT2ATDP1TTR
Lactofen SCHEMBL7577627 0.88 MEN1 (0.47) THRBMEN1KMT2ATDP1TTR
Dimethenamid SCHEMBL7585029 0.88 MEN1 (0.47) THRBMEN1KMT2ATDP1TTR
Bifenox SCHEMBL7578332 0.81 TDP1 (0.59) THRBMEN1KMT2ATDP1TTR
Oxyfluorfen SCHEMBL7581146 0.81 KMT2A (0.39) MEN1KMT2ATDP1TTRPPOX
Dimethenamid SCHEMBL7585562 0.81 THRB (0.51) THRBMEN1KMT2ATDP1TTR
Oxyfluorfen SCHEMBL7581166 0.80 MEN1 (0.40) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL7585512 0.80 MEN1 (0.49) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL7582638 0.80 MEN1 (0.58) THRBMEN1KMT2ATDP1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT THRB 2326/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.