Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28088766 | 0.70 | TOP2A (0.47) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL10365364 | 0.70 | TOP2A (0.47) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL5707874 | 0.70 | FNTA (0.41) | TOP2AKMT2ATDP1ALDH1A1RECQL | |
| SCHEMBL29172183 | 0.69 | HDAC1 (0.43) | TOP2ATOP2BMEN1KMT2A | |
| SCHEMBL30158385 | 0.69 | TOP2A (0.43) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL5707890 | 0.68 | ESR1 (0.67) | TDP1ALDH1A1RECQLGAATARBP2 | |
| SCHEMBL7561044 | 0.67 | TOP2A (0.47) | TOP2ATOP2BMEN1KMT2ANPC1 | |
| SCHEMBL11137789 | 0.66 | MEN1 (0.47) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11134767 | 0.66 | MEN1 (0.47) | TOP2ATOP2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11134339 | 0.66 | ACHE (0.46) | TOP2ATOP2BALDH1A1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106875-C | Dispersing agent | EFKA CHEMIALS B V (NL) | 2003-04-30 | — | — | CN | disclosed |
| EP-0956153-B1 | DISPERSING AGENT | EFKA ADDITIVES B V (NL) | 2002-10-02 | — | — | EP | disclosed |
| CN-1213987-A | Dispersing agent | EKFA CHEMICALS B V (NL) | 1999-04-14 | — | — | CN | disclosed |
| US-5882393-A | REACTION PRODUCT OF POLYISOCYANATES WITH A COMPOUND OF RING STRUCTURE WITH AT LEAST ONE NITROGEN ATOM IN RING; LACQUER | EFKA CHEMICALS B.V. (NL) | 1999-03-16 | — | — | US | disclosed |