Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906545 | 0.80 | LMNA (0.45) | NPC1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7573616 | 0.80 | NPC1 (0.41) | NPC1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7571865 | 0.80 | PYCR1 (0.34) | LMNAKMT2APYCR1ALDH1A1 | |
| SCHEMBL7579213 | 0.80 | NPC1 (0.50) | NPC1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL7575169 | 0.80 | MAOB (0.47) | LMNAMEN1KMT2AHPGDMAPT | |
| SCHEMBL13107935 | 0.79 | LMNA (0.46) | NPC1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3444467 | 0.79 | LMNA (0.46) | NPC1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3444466 | 0.79 | LMNA (0.46) | NPC1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14447655 | 0.78 | NPC1 (0.36) | NPC1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7573586 | 0.78 | NPSR1 (0.45) | LMNAMEN1KMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |