Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573616 | 0.80 | NPC1 (0.41) | PYCR1KMT2ACA12CA2CA9 | |
| SCHEMBL7581382 | 0.80 | NPC1 (0.40) | PYCR1KMT2AALDH1A1LMNA | |
| SCHEMBL7579213 | 0.80 | NPC1 (0.50) | PYCR1KMT2AALDH1A1CA12CA2 | |
| SCHEMBL7575169 | 0.80 | MAOB (0.47) | PYCR1KMT2ACA12CA2CA9 | |
| SCHEMBL13107935 | 0.79 | LMNA (0.46) | KMT2ACA12CA2CA9LMNA | |
| SCHEMBL3444467 | 0.79 | LMNA (0.46) | KMT2ACA12CA2CA9LMNA | |
| SCHEMBL3444466 | 0.79 | LMNA (0.46) | KMT2ACA12CA2CA9LMNA | |
| SCHEMBL7575213 | 0.77 | MAOA (0.42) | KMT2AALDH1A1CA12CA2CA9 | |
| SCHEMBL7581530 | 0.76 | MAPT (0.46) | PYCR1KMT2AALDH1A1CA12CA2 | |
| SCHEMBL20115842 | 0.76 | ALDH1A1 (0.35) | KMT2AALDH1A1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |