SCHEMBL1553905

SCHEMBL1553905

CC(C)(Br)C(=O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.56
SRD5A2 P31213 4/20 0.55
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
KMT2A Q03164 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
POLB P06746 1/20 0.49
HSP90AA1 P07900 1/20 0.49
ERCC5 P28715 1/20 0.49
FEN1 P39748 1/20 0.49
HPGD P15428 2/20 0.48
MAPT P10636 1/20 0.48
PPARA Q07869 1/20 0.47
PGR P06401 1/20 0.46
AKR1C3 P42330 1/20 0.46
BCL2 P10415 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446163 0.92 HPGD (0.56) PARP10SRD5A2RAB9ASMN1; SMN2ALDH1A1
SCHEMBL24799711 0.87 PARP10 (0.58) PARP10SRD5A2RAB9ASMN1; SMN2NPC1
SCHEMBL8357803 0.87 PARP10 (0.58) PARP10SRD5A2RAB9ASMN1; SMN2NPC1
SCHEMBL1554442 0.85 PARP10 (0.56) PARP10SRD5A2RAB9ASMN1; SMN2NPC1
SCHEMBL6682185 0.84 AKR1C3 (0.64) PARP10RAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL20612798 0.82 SRD5A2 (0.66) PARP10SRD5A2RAB9ANPC1ALDH1A1
SCHEMBL758154 0.82 CES1 (0.56) ALDH1A1L3MBTL1POLBMAPT
SCHEMBL11530017 0.81 PARP10 (0.51) PARP10SRD5A2RAB9ASMN1; SMN2NPC1
SCHEMBL10941467 0.81 SRD5A2 (0.64) PARP10SRD5A2POLBBCL2MCL1
SCHEMBL1554858 0.81 HPGD (0.44) PARP10RAB9ASMN1; SMN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL PARP10 1908/4885SRD5A2 4185/4885RAB9A 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.