Oxyfluorfen

Oxyfluorfen

SCHEMBL7581589

CCNc1nc(Cl)nc(NC(C)C)n1.CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.C[S+](C)C.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
TTR P02766 1/20 0.33
PPOX P50336 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyfluorfen SCHEMBL7584704 0.95 MEN1 (0.32) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Oxyfluorfen SCHEMBL7584389 0.95 LMNA (0.34) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Acifluorfen SCHEMBL7581374 0.94 MEN1 (0.40) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Oxyfluorfen SCHEMBL7577427 0.92 MEN1 (0.38) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Oxyfluorfen SCHEMBL7576701 0.92 KMT2A (0.37) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Metolachor SCHEMBL7584266 0.92 MEN1 (0.34) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Lactofen SCHEMBL7580609 0.92 MEN1 (0.34) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Oxyfluorfen SCHEMBL7584855 0.91 MEN1 (0.33) LMNASMN1; SMN2MEN1KMT2AALDH1A1
Oxyfluorfen SCHEMBL7575162 0.90
Acifluorfen SCHEMBL7577300 0.90 MEN1 (0.39) LMNASMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT LMNA 3881/4885SMN1; SMN2 4618/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.