SCHEMBL758165

SCHEMBL758165

C=CC[Si](CC=C)(CC=C)CCCCl

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL387076 0.77
SCHEMBL4779247 0.76
SCHEMBL28226453 0.75
SCHEMBL3698164 0.75
SCHEMBL927497 0.74 TSHR (0.33) TSHR
SCHEMBL28411664 0.74
SCHEMBL19863304 0.74 TSHR (0.43) ALDH1A1TSHR
SCHEMBL8047506 0.74 TSHR (0.33) TSHR
SCHEMBL8047247 0.74
SCHEMBL6699368 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130060014-A1 SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-03-07 US disclosed
US-20130060014-A1 SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-03-07 US disclosed
EP-1917221-B1 SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF UNIV YONSEI IACF (KR) 2012-03-21 EP disclosed
US-20090270590-A1 Surface Modified Inorganic Material and Producing Method Thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2009-10-29 US disclosed
US-20090270590-A1 Surface Modified Inorganic Material and Producing Method Thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2009-10-29 US disclosed
EP-1917221-A1 SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF Industry-Academic Cooperation Foundation, Yonsei University (KR) 2008-05-07 EP disclosed
WO-2007024055-A1 SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2007-03-01 WO disclosed
EP-0873189-B1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING & MFG (US) 2000-09-06 EP disclosed
US-5968652-A Silane coated particle 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-10-19 US disclosed
US-5876595-A OLEFINIC SILANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-02 US disclosed
EP-0873189-A1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-28 EP disclosed
US-5667674-A POLYCARBOSILANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
WO-1997025140-A1 ADSORPTION MEDIUM AND METHOD OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270590-A1 Surface Modified Inorganic Material and Producing Method Thereof ILK, ICMT, EPCAM ALDH1A1 1472/4885TSHR 4383/4885TDP1 4757/4885
US-20130060014-A1 SURFACE MODIFIED INORGANIC MATERIAL AND PRODUCING METHOD THEREOF ILK, EPCAM, CD59 ALDH1A1 1576/4885TSHR 4384/4885TDP1 4778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.