SCHEMBL7582102

SCHEMBL7582102

CCOC=C(C(=O)c1ccc(Cl)c(CSC)c1)C(=O)C1CC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 9/20 0.36
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8727304 0.85 TSHR (0.35) GRM1TSHRATM
SCHEMBL7583366 0.77 LMNA (0.30)
SCHEMBL8675635 0.77 MEN1 (0.32) GRM1TSHR
SCHEMBL9236386 0.76 KMT2A (0.47) TSHRATM
SCHEMBL9236388 0.76 KMT2A (0.47) TSHRATM
SCHEMBL8388430 0.75 MAPT (0.33)
SCHEMBL8488251 0.74 SLC6A4 (0.35) TSHRATM
SCHEMBL8488252 0.74 SLC6A4 (0.35) TSHRATM
SCHEMBL9239212 0.73 TAS1R3 (0.44) ATM
SCHEMBL9239220 0.73 TAS1R3 (0.44) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609798-B1 4-Benzoyl isoxazoles and their use as herbicides AVENTIS AGRICULTURE LTD (GB) 2002-10-02 EP disclosed
US-5374606-A Pre- and postemergence RHONE-POULENC AGRICULTURE LIMITED (GB) 1994-12-20 US disclosed
EP-0609798-A1 4-Benzoyl isoxazoles and their use as herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1994-08-10 EP disclosed