SCHEMBL7583366

SCHEMBL7583366

CCOC=C(C(=O)c1ccc(Cl)c(CSC)c1SC)C(=O)C1CC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388430 0.88 MAPT (0.33)
SCHEMBL8725799 0.84 MAPT (0.32)
SCHEMBL8754621 0.84 LMNA (0.34) LMNA
SCHEMBL8726992 0.83 HSD11B1 (0.32)
SCHEMBL8391671 0.82
SCHEMBL8754900 0.80 LMNA (0.31) LMNA
SCHEMBL8488252 0.79 SLC6A4 (0.35) LMNA
SCHEMBL8488251 0.79 SLC6A4 (0.35) LMNA
SCHEMBL7582102 0.77 GRM1 (0.36)
SCHEMBL6324660 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609798-B1 4-Benzoyl isoxazoles and their use as herbicides AVENTIS AGRICULTURE LTD (GB) 2002-10-02 EP disclosed
US-5374606-A Pre- and postemergence RHONE-POULENC AGRICULTURE LIMITED (GB) 1994-12-20 US disclosed
EP-0609798-A1 4-Benzoyl isoxazoles and their use as herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1994-08-10 EP disclosed