Logran

Logran

SCHEMBL7582408

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1.Cc1nn(-c2cc(NS(C)(=O)=O)c(Cl)cc2Cl)c(=O)n1C(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.52
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfentrazone SCHEMBL7588036 0.92 PPOX (0.54) PPOXALDH1A1KDM4ENPC1MAPT
Logran SCHEMBL7586332 0.91 PPOX (0.43) PPOXMAPT
Chlorsulfuron SCHEMBL7590529 0.91 PPOX (0.59) PPOXALDH1A1KDM4ENPC1MAPT
Sulfentrazone SCHEMBL7588596 0.88 PPOX (0.56) PPOXALDH1A1KDM4ENPC1MAPT
Prosulfuron SCHEMBL7588996 0.86 PPOX (0.52) PPOXALDH1A1KDM4ENPC1MAPT
Thifensulfuron-Methyl SCHEMBL7578954 0.83 PPOX (0.54) PPOX
Iodosulfuron SCHEMBL7589503 0.83 PPOX (0.54) PPOX
Sulfentrazone SCHEMBL7575852 0.83 PPOX (0.54) PPOX
Chlorsulfuron SCHEMBL7582744 0.83 PPOX (0.46) PPOXALDH1A1KDM4ENPC1MAPT
Carfentrazone-Ethyl SCHEMBL7585882 0.82 MAPT (0.38) ALDH1A1KDM4ENPC1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885ALDH1A1 812/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.