Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164900 | 0.83 | ALDH1A1 (0.43) | CLCN2ALDH1A1LMNATDP1KDM4E | |
| SCHEMBL7576854 | 0.82 | PTGS2 (0.51) | CLCN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7576888 | 0.80 | CLCN2 (0.50) | CLCN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7598789 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNATDP1KDM4EMEN1 | |
| SCHEMBL7583004 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNATDP1KDM4EMEN1 | |
| SCHEMBL7573910 | 0.78 | ATM (0.46) | ALDH1A1LMNATDP1KDM4EMEN1 | |
| SCHEMBL360635 | 0.78 | CXCL8 (0.45) | ALDH1A1LMNAMEN1KMT2AAKR1C3 | |
| SCHEMBL7573747 | 0.77 | F2 (0.46) | CLCN2ALDH1A1LMNATDP1KDM4E | |
| SCHEMBL11271011 | 0.76 | CXCL8 (0.44) | ALDH1A1LMNAMEN1KMT2AAKR1C3 | |
| SCHEMBL6809250 | 0.76 | CXCL8 (0.44) | ALDH1A1LMNAMEN1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |