SCHEMBL7582479

SCHEMBL7582479

COC(=O)c1ccc(C(Br)Br)c(C(Br)Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA12 O43570 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
XDH P47989 1/20 0.52
ALDH1A1 P00352 6/20 0.47
MAPT P10636 4/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 3/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NOTUM Q6P988 1/20 0.46
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15300311 0.86 NOTUM (0.55) CA1CA2CA12CA7CA9
SCHEMBL5112106 0.86 NOTUM (0.51) CA1CA2CA12CA7CA9
SCHEMBL22746852 0.84 ALDH1A1 (0.54) CA1CA2CA12CA7CA9
SCHEMBL3656263 0.84 ALDH1A1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL17978941 0.80 NOTUM (0.61) CA1CA2CA12CA7CA9
SCHEMBL22747129 0.80 CA1 (0.44) CA1CA2CA12CA7CA9
SCHEMBL13220716 0.79 CA1 (0.53) CA1CA2CA12CA7CA9
SCHEMBL7087722 0.79 VCAM1 (0.55) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL27594635 0.77 NOTUM (0.54) CA1CA2CA12CA7CA9
SCHEMBL27664817 0.77 KDM4E (0.51) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597389-B1 Water-soluble tetraazaporphins and fluorochrome for labeling HITACHI CHEMICAL CO LTD (JP) 2002-10-02 EP disclosed
US-5665875-A Water-soluble tetraazaporphins and fluorochrome for labeling HITACHI CHEMICAL CO., LTD. (JP) 1997-09-09 US disclosed
US-5627028-A Water-soluble tetraazaporphins and fluorochrome for labeling HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-05-06 US disclosed
EP-0502723-B1 Water-soluble tetraazaporphins and fluorochrome for labeling HITACHI CHEMICAL CO LTD (JP) 1996-10-09 EP disclosed
EP-0464959-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1995-12-20 EP disclosed
US-5438135-A Fluorescence analysis HITACHI CHEMICAL COMPANY (JP) 1995-08-01 US disclosed
EP-0284370-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-22 EP disclosed
EP-0597389-A1 Water-soluble tetraazaporphins and fluorochrome for labeling HITACHI CHEMICAL COMPANY, LTD. (JP) 1994-05-18 EP disclosed
US-5219706-A Naphthalocyanine derivative and production process thereof, as well as optical information recording media using the derivatives and production process thereof HITACHI, LTD. (JP) 1993-06-15 US disclosed
EP-0502723-A2 Water-soluble tetraazaporphins and fluorochrome for labeling HITACHI CHEMICAL CO., LTD. (JP) 1992-09-09 EP disclosed
EP-0284369-B1 5- OR 6-ALKOXYCARBONYL-2,3-DICYANONAPHTHALENES AND PROCESS FOR PRODUCTION THEREOF Hitachi Chemical Co., Ltd. (JP) 1992-05-20 EP disclosed
EP-0464959-A2 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1992-01-08 EP disclosed
US-4833264-A INTERMEDIATES FOR NAPHTHALOCYANINE DYES HITACHI CHEMICAL CO., LTD. (JP) 1989-05-23 US disclosed
EP-0284369-A2 5- or 6-alkoxycarbonyl-2,3-dicyanonaphthalenes and process for production thereof Hitachi Chemical Co., Ltd. (JP) 1988-09-28 EP disclosed
EP-0284370-A2 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1988-09-28 EP disclosed