SCHEMBL758255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12239024	0.90	ST14 (0.50)	ROCK2ROCK1TAAR1MAOBST14
	SCHEMBL12238998	0.84	ROCK2 (0.51)	ROCK2ROCK1TAAR1MAOBST14
	SCHEMBL921313	0.83	ROCK2 (0.50)	ROCK2ROCK1MAOBST14AKT1
	SCHEMBL12238990	0.83	ROCK2 (0.48)	ROCK2ROCK1TAAR1ST14AKT1
	SCHEMBL855493	0.83	KDM4E (0.53)	RAB9ACYP1A2CYP3A4TSHRNFKB1
	SCHEMBL29729049	0.83	KDM4E (0.53)	RAB9ACYP1A2CYP3A4TSHRNFKB1
	SCHEMBL14662168	0.82	ROCK2 (0.55)	ROCK2ROCK1TAAR1MAOBST14
	Hydrochloric Acid SCHEMBL3562522	0.81	KDM4E (0.52)	TAAR1RAB9ACYP1A2CYP3A4TSHR
	SCHEMBL13904121	0.81	ROCK2 (0.49)	ROCK2ROCK1TAAR1ST14AKT1
	SCHEMBL10121117	0.80	L3MBTL1 (0.51)	TAAR1MAOBST14RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.