SCHEMBL7582584

SCHEMBL7582584

CS(=O)(=O)c1cc(Cl)ccc1C(=O)c1cnoc1C1CC1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
FFAR1 O14842 5/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
TTR P02766 1/20 0.36
PPOX P50336 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ABCB11 O95342 1/20 0.34
THRB P10828 1/20 0.33
DHODH Q02127 1/20 0.32
HTR2B P41595 1/20 0.32
SLC6A9 P48067 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
PPARG P37231 1/20 0.31
CRHR1 P34998 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoxaflutole SCHEMBL7587808 0.97 FFAR1 (0.38) LMNAKDM4EGAAMAPTHPGD
Glyphosate SCHEMBL7583325 0.91 KDM4E (0.33) LMNAKDM4EGAAMAPTHPGD
Glufosinate SCHEMBL7580619 0.91 FFAR1 (0.32) LMNAKDM4EGAAMAPTHPGD
Glyphosate SCHEMBL7582725 0.89 KDM4E (0.31) LMNAKDM4EGAAMAPTHPGD
Isoxaflutole SCHEMBL7584358 0.88 LMNA (0.34) LMNAKDM4EGAAMAPTHPGD
Isoxaflutole SCHEMBL7587079 0.88 FFAR1 (0.33) LMNAKDM4EGAAMAPTHPGD
Isoxaflutole SCHEMBL7590294 0.86 KDM4E (0.32) LMNAKDM4EGAAMAPTHPGD
Lactofen SCHEMBL7576155 0.85 TDP1 (0.44) LMNAKDM4EGAAMAPTHPGD
Acifluorfen SCHEMBL7584738 0.83 TDP1 (0.59) LMNAKDM4EMAPTHPGDFFAR1
Isoxaflutole SCHEMBL7583603 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT LMNA 3881/4885KDM4E 1886/4885GAA 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.