Acifluorfen

Acifluorfen

SCHEMBL7582284

CON(C)C(=O)Nc1ccc(Oc2ccc3c(c2)OC(C)(OC)CC3(C)C)cc1.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
TDP1 Q9NUW8 3/20 0.54
MEN1 O00255 3/20 0.54
TTR P02766 1/20 0.54
PPOX P50336 1/20 0.54
PYGL P06737 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
FFAR1 O14842 5/20 0.34
MAPT P10636 4/20 0.34
LMNA P02545 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
CCR6 P51684 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
HPGD P15428 1/20 0.33
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fomesafen SCHEMBL7585363 0.92 KMT2A (0.44) KMT2ATDP1MEN1TTRPPOX
Acifluorfen SCHEMBL7580007 0.91 TDP1 (0.44) KMT2ATDP1MEN1TTRPPOX
Oxyfluorfen SCHEMBL7577041 0.90 MEN1 (0.41) KMT2ATDP1MEN1TTRPPOX
SCHEMBL7578167 0.90 KMT2A (0.43) KMT2ATDP1MEN1TTRPPOX
Lactofen SCHEMBL7580953 0.89 KMT2A (0.41) KMT2ATDP1MEN1TTRPPOX
Bifenox SCHEMBL7582687 0.87 TDP1 (0.56) KMT2ATDP1MEN1TTRPPOX
Fomesafen SCHEMBL7586136 0.87 TDP1 (0.40) KMT2ATDP1MEN1TTRPPOX
Oxyfluorfen SCHEMBL7585093 0.85 MEN1 (0.37) KMT2ATDP1MEN1TTRPPOX
Fomesafen SCHEMBL7583706 0.85 TDP1 (0.38) KMT2ATDP1MEN1TTRPPOX
SCHEMBL7581631 0.85 FFAR1 (0.37) KMT2ATDP1MEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885TDP1 1969/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.