SCHEMBL7582689

SCHEMBL7582689

CC(C)(C)NC(=O)O[C@H]1CNCCN1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
GBA1 P04062 1/20 0.32
SSTR4 P31391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28084531 0.81 L3MBTL1 (0.37) L3MBTL1GBA1
SCHEMBL27987055 0.79
SCHEMBL7583693 0.77 CHRNB2 (0.32)
SCHEMBL1441784 0.76 CHRM3 (0.35) L3MBTL1SSTR4
SCHEMBL954529 0.76 CHRM3 (0.35) L3MBTL1SSTR4
SCHEMBL954528 0.76 CHRM3 (0.35) L3MBTL1SSTR4
SCHEMBL7590352 0.76
SCHEMBL29291158 0.76
SCHEMBL1351693 0.76 CHRM2 (0.33)
Hydrochloric Acid SCHEMBL28057619 0.75 DPP4 (0.35) L3MBTL1SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0803502-B1 Process for the preparation of optically active piperazine-2-carboxylic acid derivatives LONZA AG (CH) 2002-06-26 EP disclosed
EP-0803502-A2 Process for the preparation of optically active piperazine-2-carboxylic acid derivatives LONZA AG (CH) 1997-10-29 EP disclosed