Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTPRG | P23470 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576061 | 0.88 | KMT2A (0.36) | ALDH1A1TP53TSHRKMT2AHTT | |
| SCHEMBL7576186 | 0.85 | ABL1 (0.39) | ALDH1A1SMN1; SMN2TSHRKMT2AHTT | |
| SCHEMBL8391826 | 0.77 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL8387656 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL8492600 | 0.74 | TSHR (0.47) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| Hexane SCHEMBL8729907 | 0.72 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL8748125 | 0.72 | LMNA (0.38) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL8392025 | 0.72 | KMT2A (0.37) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL8389398 | 0.71 | SORT1 (0.42) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL28743557 | 0.71 | CYP1A2 (0.50) | ALDH1A1SMN1; SMN2TSHRCASP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |