Fluometuron

Fluometuron

SCHEMBL7582828

C#CCN1C(=O)COc2cc(F)c(/N=c3\snc4n3CC(C)(C)C4)cc21.CN(C)C(=O)Nc1cccc(C(F)(F)F)c1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 5/20 0.39
MAPT P10636 5/20 0.39
EGFR P00533 1/20 0.34
CXCR3 P49682 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32
LMNA P02545 1/20 0.32
UBE2M P61081 1/20 0.31
DCUN1D1 Q96GG9 1/20 0.31
CHUK O15111 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorotoluron SCHEMBL7585958 0.88 MAPT (0.36) TP53MAPTEGFRPOLBMEN1
Isoproturon SCHEMBL7578742 0.87 MAPT (0.35) MAPTPOLB
SCHEMBL29462399 0.84 CHRM1 (0.31)
SCHEMBL39404 0.84 CHRM1 (0.31)
SCHEMBL5420505 0.84 CHRM1 (0.31)
Dimefuron SCHEMBL7578599 0.83 MEN1 (0.49) MEN1KMT2A
Thidiazuron SCHEMBL7590312 0.81 TDP1 (0.31) POLB
Phenmedipham SCHEMBL7578867 0.81 FAAH (0.38) TP53MAPTEGFRPOLB
Desmedipham SCHEMBL7585507 0.80 BCHE (0.33) TP53MAPTPOLBMEN1KMT2A
Pyrazole SCHEMBL8003649 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TP53 4303/4885MAPT 1092/4885EGFR 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.