Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | CASR | P41180 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167943 | 0.93 | SMN1; SMN2 (0.96) | SMN1; SMN2CASRPOLBHTTMEN1 | |
| SCHEMBL27838298 | 0.93 | SMN1; SMN2 (0.96) | SMN1; SMN2CASRPOLBHTTMEN1 | |
| SCHEMBL11881252 | 0.92 | SMN1; SMN2 (0.70) | SMN1; SMN2CASRPOLBHTTSIGMAR1 | |
| SCHEMBL11877256 | 0.90 | SMN1; SMN2 (0.79) | SMN1; SMN2CASRPOLBMEN1KMT2A | |
| SCHEMBL29560 | 0.88 | SMN1; SMN2 (0.76) | SMN1; SMN2CASRPOLBHTTSIGMAR1 | |
| SCHEMBL79765 | 0.88 | SMN1; SMN2 (0.76) | SMN1; SMN2CASRPOLBHTTSIGMAR1 | |
| SCHEMBL774613 | 0.88 | SMN1; SMN2 (0.76) | SMN1; SMN2CASRPOLBHTTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9635019 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2CASRPOLBHTTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL27830673 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2CASRPOLBHTTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL5493749 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2CASRPOLBHTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193636-A1 | Benzaldehyde reacted with a primary amine to give an imine, which is hydrogenated with hydrogen in the presence of a catalyst and a water miscible solvent | BASF AKTIENGESELLCHAFT (DE) | 2002-12-19 | — | — | US | disclosed |
| US-6476268-B1 | Preparation of N-benzylamines | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-05 | — | — | US | disclosed |
| EP-1247799-A2 | Process for the preparation of N-benzylamines | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193636-A1 | Benzaldehyde reacted with a primary amine to give an imine, which is hydrogenated with hydrogen in the presence of a catalyst and a water miscible solvent | HNMT, INMT, H1-2 | SMN1; SMN2 756/4885CASR 4693/4885POLB 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.