SCHEMBL75829

SCHEMBL75829

C=Cc1cccc2c1ccc1ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.58
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP2A6 P11509 1/20 0.50
TSHR P16473 1/20 0.50
PAX8 Q06710 1/20 0.43
CYP1A2 P05177 2/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
THRB P10828 1/20 0.43
HPGD P15428 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
CYP3A4 P08684 2/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
APEX1 P27695 1/20 0.40
MAPK1 P28482 1/20 0.40
PMP22 Q01453 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2701066 1.00 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL31610342 0.87 SIRT2 (0.50) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL29357296 0.87 SIRT2 (0.50) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL6863260 0.87 SIRT2 (0.50) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL14912 0.87 SIRT2 (0.50) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL5888918 0.86 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL28814531 0.86 HSD17B10 (0.54) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL28110259 0.85 ALDH1A1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
Ammonia Solution, Strong SCHEMBL1824430 0.85 SIRT2 (0.49) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL18141098 0.85 SIRT2 (0.49) ALDH1A1HSD17B10TDP1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
CN-119081008-B High-frequency low-dielectric-loss benzocyclobutene resin and preparation method and application thereof 四川涪立芯材料科技有限公司 2025-03-07 CN claimed
CN-119081008-A High-frequency low-dielectric-loss benzocyclobutene resin and preparation method and application thereof 四川涪立芯材料科技有限公司 2024-12-06 CN claimed
CN-115989251-B Composition comprising an additive having polycyclic aromatic groups 伊英克公司 2024-08-23 CN claimed
EP-3443055-B1 REMOVING AROMATIC COMPOUNDS FROM A HYDROCARBON FLUID CASTROL LTD (GB) 2024-07-03 EP claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
EP-3554830-B1 HIGH-CHI BLOCK COPOLYMERS FOR DIRECTED SELF-ASSEMBLY BREWER SCIENCE INC (US) 2023-10-18 EP claimed
CN-115989251-A Composition comprising an additive having polycyclic aromatic groups 伊英克公司 2023-04-18 CN claimed
US-5986024-A POLYMERIZATION CATALYSTS WITH CYCLOPENTADIENE METAL CATALYST SRI INTERNATIONAL (US) 1999-11-16 US claimed
WO-1999020665-A1 PREPARATION OF MULTIMODAL POLYMER COMPOSITIONS USING MULTINUCLEAR METALLOCENE CATALYSTS SRI INTERNATIONAL (US) 1999-04-29 WO claimed
EP-0593462-B1 METHOD FOR UPGRADING STEAM CRACKER TARS EXXON CHEMICAL PATENTS INC (US) 1996-03-06 EP claimed
US-5441849-A Reduces electrical charge accumulation caused by an exposure to charged particle beam HITACHI, LTD. (JP) 1995-08-15 US claimed
US-5334665-A Dispersant for carbon black, graphite; flow control agents BRIDGESTONE/FIRESTONE, INC. (US) 1994-08-02 US claimed
EP-0593462-A1 METHOD FOR UPGRADING STEAM CRACKER TARS. EXXON CHEMICAL PATENTS INC (US) 1994-04-27 EP claimed
US-5215649-A METHOD FOR UPGRADING STEAM CRACKER TARS EXXON CHEMICAL PATENTS INC. (US) 1993-06-01 US claimed
US-5210144-A Polymers for tire tread BRIDGESTONE CORPORATION (JP) 1993-05-11 US claimed
US-5210145-A Tires, reduced rolling resistance BRIDGESTONE/FIRESTONE, INC. (US) 1993-05-11 US claimed
WO-1991017230-A1 METHOD FOR UPGRADING STEAM CRACKER TARS EXXON CHEMICAL PATENTS INC. (US) 1991-11-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA HPRT1 4795/4885ALDH1A1 1323/4885HSD17B10 3823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.