SCHEMBL7583029

SCHEMBL7583029

C[C@@H](Oc1ccc(Oc2ccc(C#N)cc2F)cc1)C(=O)O.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.47
PTGDR2 Q9Y5Y4 3/20 0.45
MEN1 O00255 1/20 0.42
TTR P02766 1/20 0.42
PPOX P50336 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MRGPRX4 Q96LA9 2/20 0.38
LMNA P02545 2/20 0.37
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
CYP11B1 P15538 1/20 0.37
THRB P10828 1/20 0.37
SCN8A Q9UQD0 1/20 0.36
SCN10A Q9Y5Y9 1/20 0.36
SCN9A Q15858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7586913 0.85 TDP1 (0.65) FFAR1PTGDR2MEN1TTRPPOX
SCHEMBL15844933 0.85 FFAR1 (0.56) FFAR1PTGDR2MEN1TTRPPOX
SCHEMBL2681468 0.85 FFAR1 (0.56) FFAR1PTGDR2MEN1TTRPPOX
SCHEMBL39100 0.85 FFAR1 (0.56) FFAR1PTGDR2MEN1TTRPPOX
SCHEMBL4889531 0.85 FFAR1 (0.56) FFAR1PTGDR2MEN1TTRPPOX
Ioxynil SCHEMBL7588365 0.84 FFAR1 (0.45) FFAR1PTGDR2MEN1TTRPPOX
Bromoxynil SCHEMBL7587672 0.83 FFAR1 (0.44) FFAR1PTGDR2MEN1TTRPPOX
Clodinafop SCHEMBL7578270 0.82 FFAR1 (0.44) FFAR1MEN1TTRPPOXKMT2A
Fluazifop SCHEMBL7578044 0.82 FFAR1 (0.46) FFAR1MEN1TTRPPOXKMT2A
Diclofop-Methyl SCHEMBL7579170 0.81 FFAR1 (0.47) FFAR1PTGDR2MEN1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885PTGDR2 3560/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.