Aclonifen

Aclonifen

SCHEMBL7583380

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccsc2C(=O)O)n1.C[S+](C)C.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
TTR P02766 1/20 0.36
ALB P02768 1/20 0.36
THRB P10828 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TBXA2R P21731 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aclonifen SCHEMBL7586062 0.94 MEN1 (0.38) MEN1TTRALBTHRBKMT2A
Aclonifen SCHEMBL7580623 0.90 MEN1 (0.45) MEN1TTRALBTHRBKMT2A
Prosulfuron SCHEMBL7577518 0.87 MEN1 (0.35) MEN1TTRALBTHRBKMT2A
Thifensulfuron-Methyl SCHEMBL7583365 0.85 MEN1 (0.44) MEN1TTRALBTHRBKMT2A
Aclonifen SCHEMBL7577790 0.85 MEN1 (0.36) MEN1TTRALBTHRBKMT2A
Bifenox SCHEMBL7581471 0.85 TDP1 (0.43) MEN1TTRKMT2ATDP1TBXA2R
Acifluorfen SCHEMBL7584458 0.83 TDP1 (0.44) MEN1TTRKMT2ATDP1TBXA2R
Prosulfuron SCHEMBL7575876 0.83 MEN1 (0.31) MEN1TTRALBTHRBKMT2A
Aclonifen SCHEMBL7585692 0.83 KMT2A (0.35) MEN1TTRALBTHRBKMT2A
Oxyfluorfen SCHEMBL7585610 0.82 MEN1 (0.36) MEN1TTRKMT2ATDP1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885TTR 1945/4885ALB 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.