Oxyfluorfen

Oxyfluorfen

SCHEMBL7583682

CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.42
MEN1 O00255 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
TTR P02766 1/20 0.42
PPOX P50336 1/20 0.42
JMJD7 P0C870 1/20 0.39
MAPT P10636 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
LMNA P02545 2/20 0.37
ALOX12 P18054 1/20 0.37
CCR6 P51684 1/20 0.37
GAA P10253 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PKM P14618 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
FFAR1 O14842 2/20 0.35
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7587596 0.92 KMT2A (0.53) KMT2AMEN1TDP1TTRPPOX
Lactofen SCHEMBL7575654 0.90 KMT2A (0.44) KMT2AMEN1TDP1TTRPPOX
Diclofop-Methyl SCHEMBL7588097 0.90 KMT2A (0.44) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL14655345 0.89 KMT2A (0.52) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7580501 0.89 KMT2A (0.43) KMT2AMEN1TDP1TTRPPOX
Fomesafen SCHEMBL7585215 0.89 KMT2A (0.44) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7590222 0.87 MEN1 (0.52) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7583155 0.87 KMT2A (0.40) KMT2AMEN1TDP1TTRPPOX
Diclofop-Methyl SCHEMBL7580344 0.86 TDP1 (0.56) KMT2AMEN1TDP1TTRPPOX
Diclofop-Methyl SCHEMBL7586776 0.84 JMJD7 (0.36) KMT2AMEN1TDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.