Diclofop-Methyl

Diclofop-Methyl

SCHEMBL7586776

COC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JMJD7 P0C870 1/20 0.36
KMT2A Q03164 6/20 0.35
MEN1 O00255 5/20 0.35
MAPT P10636 5/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
LMNA P02545 4/20 0.35
NPSR1 Q6W5P4 2/20 0.35
ALOX12 P18054 2/20 0.35
CCR6 P51684 1/20 0.35
TDP1 Q9NUW8 4/20 0.34
TTR P02766 1/20 0.34
PPOX P50336 1/20 0.34
PKM P14618 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GAA P10253 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diclofop-Methyl SCHEMBL7587639 0.87 TDP1 (0.43) KMT2AMEN1MAPTL3MBTL1LMNA
Clodinafop SCHEMBL7586800 0.86 L3MBTL1 (0.35) JMJD7KMT2AMEN1MAPTL3MBTL1
Mecoprop SCHEMBL7578934 0.86 KMT2A (0.41) JMJD7KMT2AMEN1MAPTL3MBTL1
Acifluorfen SCHEMBL7587596 0.85 KMT2A (0.53) JMJD7KMT2AMEN1MAPTL3MBTL1
Oxyfluorfen SCHEMBL7583682 0.84 KMT2A (0.42) JMJD7KMT2AMEN1MAPTL3MBTL1
Fomesafen SCHEMBL7585215 0.83 KMT2A (0.44) JMJD7KMT2AMEN1MAPTL3MBTL1
Diclofop-Methyl SCHEMBL7582950 0.82 KMT2A (0.43) JMJD7KMT2AMEN1MAPTL3MBTL1
Diclofop-Methyl SCHEMBL7588097 0.81 KMT2A (0.44) JMJD7KMT2AMEN1MAPTL3MBTL1
Lactofen SCHEMBL7575654 0.81 KMT2A (0.44) JMJD7KMT2AMEN1MAPTL3MBTL1
Diclofop-Methyl SCHEMBL7580344 0.81 TDP1 (0.56) JMJD7KMT2AMEN1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT JMJD7 789/4885KMT2A 2099/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.