Napropamide

Napropamide

SCHEMBL7584129

CCN(CC)C(=O)C(C)Oc1cccc2ccccc12.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.42
SCN9A Q15858 4/20 0.40
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.37
MRGPRX4 Q96LA9 4/20 0.36
HPGD P15428 2/20 0.35
ESRRA P11474 1/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
STK39 Q9UEW8 1/20 0.35
THRB P10828 1/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7582982 0.84 TDP1 (0.49) FFAR1SCN9AMEN1TTRPPOX
SCHEMBL4889531 0.82 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL15844933 0.82 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL39100 0.82 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL2681468 0.82 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7582873 0.80 MEN1 (0.47) FFAR1SCN9AMEN1TTRPPOX
Napropamide SCHEMBL7584416 0.80 TDP1 (0.48) FFAR1SCN9AMEN1TTRPPOX
SCHEMBL10644584 0.77 FFAR1 (0.50) FFAR1SCN9AMEN1TTRPPOX
Mecoprop SCHEMBL7587205 0.77 TSHR (0.53) FFAR1MEN1TTRPPOXKMT2A
Prosulfocarb SCHEMBL7578746 0.77 FFAR1 (0.45) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885SCN9A 2334/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.