Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 13/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415702 | 0.75 | GPR84 (0.51) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL3224553 | 0.70 | MPO (0.49) | GPR84MPOHTR2AHTR1AKMT2A | |
| SCHEMBL208748 | 0.70 | GPR84 (0.58) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL20584073 | 0.69 | GPR84 (0.62) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL18383118 | 0.68 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL30482437 | 0.68 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL30913603 | 0.68 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL20355068 | 0.67 | GPR84 (0.50) | GPR84HTR2A | |
| SCHEMBL7845587 | 0.67 | MPO (0.71) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL1372357 | 0.66 | GPR84 (0.58) | GPR84MPOHTR2ATRPM8HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002205983-A | INDOLE DERIVATIVE | NIPPON KAYAKU CO LTD | 2002-07-23 | — | — | JP | disclosed |