Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63468 | 0.62 | ALDH1A1 (0.67) | KIF11HTR3EHTR3BPLAUHTR3A | |
| SCHEMBL91414 | 0.60 | TSHR (0.55) | KIF11ALDH1A1TSHR | |
| SCHEMBL17816159 | 0.60 | TSHR (0.55) | KIF11ALDH1A1TSHR | |
| SCHEMBL13838853 | 0.59 | OPRL1 (0.52) | MAOAMAOBKDM1AOPRM1OPRL1 | |
| SCHEMBL25508922 | 0.59 | MAOA (0.48) | MAOAMAOBKDM1AOPRM1OPRL1 | |
| Bromide SCHEMBL27849066 | 0.58 | TSHR (0.52) | KIF11ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL28559843 | 0.58 | TSHR (0.52) | KIF11ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL793057 | 0.58 | OPRL1 (0.50) | MAOAMAOBKDM1AOPRM1OPRL1 | |
| SCHEMBL677817 | 0.57 | ALDH1A1 (0.53) | KIF11ALDH1A1TSHR | |
| SCHEMBL1755260 | 0.57 | PDE2A (0.46) | KIF11ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242434-A1 | POLYMERIZATION-ACTIVE TRANSITION METAL COMPLEX COMPOUNDS COMPRISING A STERICALLY DEMANDING LIGAND SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042257-A1 | POLYMERIZATION-ACTIVE TRANSITION METAL COMPLEX COMPOUNDS COMPRISING A STERICALLY DEMANDING LIGAND SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-14 | — | — | WO | disclosed |