Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482459 | 0.83 | MEN1 (0.57) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL13240820 | 0.83 | MEN1 (0.57) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL2483519 | 0.82 | FPR2 (0.49) | MAPTFPR2ALDH1A1LMNAKDM4E | |
| SCHEMBL2483521 | 0.82 | FPR2 (0.49) | MAPTFPR2ALDH1A1LMNAKDM4E | |
| SCHEMBL146704 | 0.82 | FPR2 (0.49) | MAPTFPR2ALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL2484358 | 0.82 | MEN1 (0.56) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL2482091 | 0.81 | SMN1; SMN2 (0.53) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28534876 | 0.81 | FPR2 (0.47) | MAPTKMT2AFPR2ALDH1A1LMNA | |
| SCHEMBL7576927 | 0.80 | CRHBP (0.51) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7573687 | 0.80 | MAOA (0.48) | MAPTKMT2AFPR2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |