Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP19 | O94966 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590748 | 0.88 | POLB (0.42) | POLBUSP19PARP1MAOBPRKCB | |
| SCHEMBL1580100 | 0.83 | POLB (0.54) | POLBUSP19PARP1DPP4DPP7 | |
| SCHEMBL7582099 | 0.80 | OPRD1 (0.36) | POLBUSP19HTR2AHTR2CHTR2B | |
| SCHEMBL7581329 | 0.79 | OPRD1 (0.36) | POLBUSP19BACE1 | |
| SCHEMBL7582641 | 0.78 | POLB (0.41) | POLBUSP19 | |
| SCHEMBL14833446 | 0.77 | HTR2C (0.47) | USP19HTR2AHTR2CHTR2BROCK2 | |
| SCHEMBL14833502 | 0.76 | MMP1 (0.44) | NPC1RAB9AMAOAMAOB | |
| Tert-Butyl Formate SCHEMBL28018953 | 0.75 | POLB (0.43) | POLBUSP19HTR2AHTR2CPARP1 | |
| SCHEMBL20528485 | 0.73 | DPP4 (0.46) | POLBUSP19HTR2AHTR2CHTR2B | |
| SCHEMBL21801033 | 0.73 | DPP4 (0.46) | POLBUSP19HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | claimed |
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | claimed |
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1412661-A | Chinese character name code keyboard input method | LU YUSHAN (CN) | 2003-04-23 | — | — | CN | disclosed |
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| CN-1290700-A | Phenyl piperazine derivatives | EISAI LTD (JP) | 2001-04-11 | — | — | CN | disclosed |