Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | USP19 | O94966 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585368 | 0.88 | POLB (0.39) | POLBUSP19PARP1DPP4DPP7 | |
| SCHEMBL1580100 | 0.86 | POLB (0.54) | POLBUSP19PARP1DPP4DPP7 | |
| SCHEMBL3338258 | 0.77 | LMNA (0.44) | POLBDPP4DPP7MAOB | |
| Tert-Butyl Formate SCHEMBL28018953 | 0.75 | POLB (0.43) | POLBUSP19PARP1DPP4DPP7 | |
| SCHEMBL7749807 | 0.75 | RIPK1 (0.46) | USP19DPP4DPP7MAPK1SLC6A2 | |
| SCHEMBL20528485 | 0.75 | DPP4 (0.46) | POLBUSP19DPP4DPP7KMT2A | |
| SCHEMBL2935422 | 0.75 | DPP4 (0.46) | POLBUSP19DPP4DPP7KMT2A | |
| SCHEMBL21801033 | 0.75 | DPP4 (0.46) | POLBUSP19DPP4DPP7KMT2A | |
| Hydrochloric Acid SCHEMBL9258072 | 0.74 | DPP4 (0.46) | POLBUSP19DPP4DPP7KMT2A | |
| SCHEMBL19217307 | 0.74 | POLB (0.42) | POLBUSP19PARP1DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | claimed |
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | claimed |
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1412661-A | Chinese character name code keyboard input method | LU YUSHAN (CN) | 2003-04-23 | — | — | CN | disclosed |
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| CN-1290700-A | Phenyl piperazine derivatives | EISAI LTD (JP) | 2001-04-11 | — | — | CN | disclosed |
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | disclosed |