SCHEMBL7585579

SCHEMBL7585579

O=C(O)c1ccc2c(ccc3ccccc32)c1Br

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.61
LDHA P00338 1/20 0.59
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
HPRT1 P00492 1/20 0.52
SOS1 Q07889 2/20 0.50
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
CDC25B P30305 1/20 0.49
ALDH1A1 P00352 4/20 0.47
HPGD P15428 3/20 0.47
KDM4E B2RXH2 2/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL485599 0.90 WDR5 (0.68) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL11681567 0.84 CYP1A2 (0.50) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL11928243 0.81 WDR5 (0.61) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL183135 0.81 WDR5 (0.61) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL160289 0.81 WDR5 (0.61) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL31613859 0.81 WDR5 (0.61) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL2537370 0.81 LDHA (0.82) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL1261457 0.81 NR4A1 (0.77) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL1000484 0.81 NR4A1 (0.77) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL31186208 0.81 WDR5 (0.56) WDR5LDHANR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107573299-A It is a kind of using two phenanthro- indenes fluorenes units as bipolarity small molecule emitter material of core and preparation method and application 华南理工大学 2018-01-12 CN disclosed
CN-107365294-A A kind of bipolarity small molecule emitter material based on two phenanthro- sulphur dibenzofuran units and preparation method and application 华南理工大学 2017-11-21 CN disclosed
CN-107312163-A A kind of blue light conjugated polymer based on two phenanthro- sulphur dibenzofuran units and preparation method and application 华南理工大学 2017-11-03 CN disclosed
CN-107236116-A A kind of blue light conjugated polymer based on two phenanthro- indenes fluorenes units and preparation method and application 华南理工大学 2017-10-10 CN disclosed
CN-107162984-A A kind of bipolarity small molecule emitter material using the indenes fluorenes unit of two phenanthro- 2,8 as core and preparation method and application 华南理工大学 2017-09-15 CN disclosed
CN-107141452-A The conjugated polymer of one kind based on phenanthro- S, S dioxydibenze bithiophene unit and preparation method and application 华南理工大学 2017-09-08 CN disclosed
CN-107118201-A A kind of bipolarity small molecule emitter material based on the sulphur dibenzofuran unit of two phenanthro- 2,8 and preparation method and application 华南理工大学 2017-09-01 CN disclosed
CN-107089966-A Bipolarity small molecule emitter material and its preparation method and application of the one kind based on phenanthro- S, S dioxydibenze bithiophene unit 华南理工大学 2017-08-25 CN disclosed
EP-1244638-A2 PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 2002-10-02 EP disclosed
WO-2001044205-A2 PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 2001-06-21 WO disclosed