SCHEMBL485599

SCHEMBL485599

O=C(O)c1ccc2ccccc2c1Br

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.68
LDHA P00338 1/20 0.66
NR4A1 P22736 1/20 0.61
NR4A2 P43354 1/20 0.61
NR4A3 Q92570 1/20 0.61
POLB P06746 1/20 0.55
CDC25B P30305 1/20 0.53
ALDH1A1 P00352 4/20 0.50
HPGD P15428 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
LMNA P02545 1/20 0.49
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
NCEH1 Q6PIU2 2/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7585579 0.90 WDR5 (0.61) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL31186208 0.89 WDR5 (0.56) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL28307351 0.85 WDR5 (0.55) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL2016154 0.84 POLB (0.52) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL31520424 0.84 POLB (0.52) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL4645452 0.84 POLB (0.52) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL607844 0.84 POLB (0.52) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL10627949 0.83 WDR5 (0.49) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL29721418 0.81 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL895573 0.81 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106588869-B Dialkyl group replaces naphtho- sulphur dibenzofuran monomer and preparation method thereof and replaces polymer and its application of naphtho- sulphur dibenzofuran unit containing dialkyl group 华南理工大学 2019-07-16 CN claimed
CN-109836618-A Modification method of aluminum oxide 中国石油天然气股份有限公司 2019-06-04 CN claimed
CN-109438230-A The synthetic method of the bromo- 2- naphthoate of Adapalene intermediate 6- 深圳市第二人民医院 2019-03-08 CN claimed
CN-107954921-A A kind of electroluminescent material blocked with 9- phenyl fluorenes and preparation method and application 华南协同创新研究院 2018-04-24 CN claimed
CN-107935936-A Benzimidazole compound and derivative, Organic Electron Transport Material and its preparation and application 华南理工大学 2018-04-20 CN claimed
CN-106588869-A Dialkyl-substituted naphtho-dioxodibenzothiophene monomer and preparation method thereof and polymer containing dialkyl-substituted naphtho-dioxodibenzothiophene unit and application of polymer 华南理工大学 2017-04-26 CN claimed
CN-105541605-A Synthesis method of axially chiral dinaphthalene ligand precursor (s)-2,2'-dinaphthyl-1,1'-dicarboxylic acid UNIV YANGZHOU 2016-05-04 CN claimed
CN-103180284-B Method for producing refined 6-bromo-2-naphthalenecarboxylic acid product AIR WATER INC 2015-05-20 CN claimed
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 US disclosed
US-12378254-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2025-08-05 US disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 US disclosed
CN-118894886-A Preparation method of axial chiral alkenyl borate containing phosphine or carboxylate 福州大学 2024-11-05 CN disclosed
CN-118791407-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-10-18 CN disclosed
CN-118638096-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-09-13 CN disclosed
EP-0687249-A1 BALANOIDS ELI LILLY AND COMPANY (US) 1995-12-20 EP disclosed
WO-1994020062-A2 BALANOIDS AS PROTEIN KINASE C INHIBITORS ELI LILLY AND COMPANY (US) 1994-09-15 WO disclosed
EP-0010842-B1 POLYURETHANE FOAM AND METHOD OF PREPARATION THEREOF UNIROYAL LTD. (CA) 1983-09-21 EP disclosed
US-4224225-A PHOTOPOLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1980-09-23 US disclosed
US-4209593-A Semi-flexible shock-absorbing polyurethane foam prepared from a triol, a compound having a single reactive hydrogen, an aromatic polyisocyanate, blowing agent, chain-extender and a catalyst UNIROYAL LTD. (CA) 1980-06-24 US disclosed
EP-0010842-A1 Polyurethane foam and method of preparation thereof UNIROYAL LTD. (CA) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378254-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators HCRTR2, HCRTR1, OXTR WDR5 591/4885LDHA 3754/4885NR4A1 196/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 WDR5 1902/4885LDHA 1365/4885NR4A1 28/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B WDR5 4067/4885LDHA 1092/4885NR4A1 1925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.