SCHEMBL7586133

SCHEMBL7586133

O=C1CCCc2cc3ccccc3cc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 10/20 0.59
MAOB P27338 10/20 0.59
CYP2A6 P11509 1/20 0.59
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
PRKCI P41743 1/20 0.52
MAPK1 P28482 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
GRM5 P41594 1/20 0.51
LMNA P02545 2/20 0.49
ALDH1A1 P00352 1/20 0.49
TP53 P04637 1/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
CASP1 P29466 1/20 0.49
MPI P34949 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31643666 1.00 MAOA (0.59) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL6940637 0.88 CASP1 (0.52) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL30402712 0.88 CASP1 (0.52) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL27843881 0.84 HSD17B1 (0.51) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL27844082 0.84 HSD17B1 (0.51) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL27843799 0.80 MAOA (0.49) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL27844098 0.80 MAOA (0.49) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL27843801 0.80 MAOA (0.49) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL27843806 0.79 MAOB (0.49) MAOAMAOBCYP2A6MEN1KMT2A
SCHEMBL8284440 0.78 MEN1 (0.69) MAOAMAOBCYP2A6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62207213-A None JP disclosed
EP-2053095-B2 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
CN-102282484-A Inversely dispersive retardation film, and liquid crystal display device comprising same 2011-12-14 CN disclosed
EP-0864559-B1 Substituted amino compounds and their use as analgesic active substances GRUENENTHAL GMBH (DE) 2002-06-05 EP disclosed
US-6022895-A Substituted amino compounds and their use as substances having an analgesic effect GRUENENTHAL GMBH (DE) 2000-02-08 US disclosed
EP-0864559-A1 Substituted amino compounds and their use as analgesic active substances Grünenthal GmbH (DE) 1998-09-16 EP disclosed
JP-S62207213-A ANTICANCER AGENT TAISHO PHARMACEUT CO LTD 1987-09-11 JP disclosed