Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | ELOC | Q15369 | 1/20 | 0.40 |
| ▸ | ELOB | Q15370 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345475 | 0.73 | CA2 (0.51) | CA2KDM4EHTTVHLELOC | |
| SCHEMBL7298398 | 0.72 | GAA (0.39) | CA2 | |
| SCHEMBL10511373 | 0.72 | CA2 (0.71) | CA2KDM4EHTTVHLELOC | |
| SCHEMBL10512538 | 0.72 | CA2 (0.71) | CA2KDM4EHTTVHLELOC | |
| SCHEMBL10512165 | 0.72 | CA2 (1.00) | CA2KDM4EHTTVHLELOC | |
| SCHEMBL23042702 | 0.69 | PBRM1 (0.31) | — | |
| SCHEMBL28345538 | 0.68 | CA2 (0.47) | CA2KDM4EHTTVHLELOC | |
| SCHEMBL7287314 | 0.67 | ALDH1A1 (0.38) | KDM4EHTTALDH1A1 | |
| SCHEMBL7298799 | 0.67 | CA2 (0.45) | CA2KDM4EHTTVHLELOC | |
| SCHEMBL3138935 | 0.67 | MEN1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | NQO2, NQO1, NDUFA7 | CA2 1595/4885KDM4E 3740/4885HTT 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.