Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934449 | 1.00 | AKR1C2 (0.41) | AKR1C2AKR1C1FTOPGRESR2 | |
| SCHEMBL6932901 | 0.90 | PGR (0.41) | AKR1C2AKR1C1FTOPGRESR2 | |
| SCHEMBL7956300 | 0.88 | LMNA (0.43) | ESR2MCL1LMNANPSR1HSP90AA1 | |
| SCHEMBL6932932 | 0.86 | MDM2 (0.38) | AKR1C2AKR1C1NPSR1MAPTKMT2A | |
| SCHEMBL6026268 | 0.83 | CFTR (0.39) | AKR1C2AKR1C1ESR2MCL1LMNA | |
| SCHEMBL6931613 | 0.80 | AKR1C2 (0.42) | AKR1C2AKR1C1FTOPGRESR2 | |
| SCHEMBL7591686 | 0.80 | AKR1C2 (0.42) | AKR1C2AKR1C1FTOPGRESR2 | |
| SCHEMBL6932670 | 0.77 | MDM2 (0.38) | MCL1POLBMAPTMEN1KMT2A | |
| SCHEMBL6026391 | 0.76 | MCL1 (0.42) | ESR2MCL1LMNANPSR1HSP90AA1 | |
| SCHEMBL7966642 | 0.75 | CYP1A2 (0.41) | ESR2LMNAHSP90AA1CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246811-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS Isle of Man, Limited (GB) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049671-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS ISLE OF MAN, LIMITED (US) | 2001-07-12 | — | — | WO | disclosed |