Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932601 | 0.91 | CFTR (0.43) | CFTRGOPCALDH1A1TYMSMEN1 | |
| SCHEMBL6932901 | 0.85 | PGR (0.41) | CYP1A2CFTRGOPCALDH1A1TYMS | |
| SCHEMBL6026158 | 0.85 | CFTR (0.50) | CYP1A2CFTRGOPCALDH1A1TYMS | |
| SCHEMBL7956413 | 0.85 | CFTR (0.39) | CFTRGOPCALDH1A1TYMSMEN1 | |
| SCHEMBL6026268 | 0.85 | CFTR (0.39) | CFTRGOPCALDH1A1TYMSMEN1 | |
| SCHEMBL6026912 | 0.83 | ALDH1A1 (0.36) | CFTRGOPCALDH1A1TYMSMEN1 | |
| SCHEMBL7955988 | 0.82 | ALDH1A1 (0.37) | CFTRGOPCALDH1A1TYMSMEN1 | |
| SCHEMBL6029237 | 0.82 | PIM1 (0.41) | CFTRGOPCALDH1A1TYMSMEN1 | |
| SCHEMBL7968717 | 0.81 | KIF11 (0.46) | CYP1A2CFTRGOPCALDH1A1TYMS | |
| SCHEMBL6026464 | 0.81 | EGFR (0.43) | CFTRGOPCALDH1A1TYMSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |