Mesotrione

Mesotrione

SCHEMBL7586474

CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.CP(=O)(O)CCC(N)C(=O)O.CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.32
MEN1 O00255 1/20 0.32
TTR P02766 1/20 0.32
PPOX P50336 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7586887 0.95 MEN1 (0.33) HPDMEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7583502 0.94 MEN1 (0.39) HPDMEN1TTRPPOXKMT2A
Mesotrione SCHEMBL7590639 0.94 HPD (0.36) HPDMEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7587543 0.92 HPD (0.33) HPDMEN1TTRPPOXKMT2A
Fomesafen SCHEMBL7577351 0.92 MEN1 (0.34) HPDMEN1TTRPPOXKMT2A
Mesotrione SCHEMBL7582977 0.92
Mesotrione SCHEMBL7577643 0.92 MEN1 (0.33) HPDMEN1TTRPPOXKMT2A
Mesotrione SCHEMBL7578400 0.90 HPD (0.32) HPDMEN1TTRPPOXKMT2A
Mesotrione SCHEMBL7581220 0.89 HPD (0.31) HPDMEN1TTRPPOXKMT2A
Mesotrione SCHEMBL7587975 0.88 HPD (0.41) HPDMEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT HPD 7/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.