Dimefuron

Dimefuron

SCHEMBL7586528

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CN(C)C(=O)Nc1ccc(-n2nc(C(C)(C)C)oc2=O)c(Cl)c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.52
TDP1 Q9NUW8 3/20 0.52
MEN1 O00255 3/20 0.52
PPOX P50336 11/20 0.43
TTR P02766 1/20 0.43
MAPT P10636 2/20 0.33
THRB P10828 1/20 0.33
VDR P11473 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
EGFR P00533 2/20 0.33
ERBB2 P04626 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7587915 0.89 TDP1 (0.58) KMT2ATDP1MEN1PPOXTTR
Oxyfluorfen SCHEMBL7578497 0.88 MEN1 (0.57) KMT2ATDP1MEN1PPOXTTR
Oxadiazon SCHEMBL7576763 0.86 PPOX (0.49) KMT2ATDP1MEN1PPOXTTR
Dcmu SCHEMBL7585430 0.85 KMT2A (0.53) KMT2ATDP1MEN1PPOXTTR
Chlorotoluron SCHEMBL7583760 0.85 KMT2A (0.53) KMT2ATDP1MEN1PPOXTTR
SCHEMBL7580739 0.84 PPOX (0.44) KMT2ATDP1MEN1PPOXTTR
Dimefuron SCHEMBL7577966 0.84 KMT2A (0.60) KMT2ATDP1MEN1PPOXTTR
Fluometuron SCHEMBL7584265 0.83 KMT2A (0.53) KMT2ATDP1MEN1PPOXTTR
Isoproturon SCHEMBL7583238 0.82 KMT2A (0.52) KMT2ATDP1MEN1PPOXTTR
Dimefuron SCHEMBL7579678 0.79 MEN1 (0.57) KMT2ATDP1MEN1PPOXTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885TDP1 1969/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.