Dimefuron

Dimefuron

SCHEMBL7577966

CN(C)C(=O)Nc1ccc(-n2nc(C(C)(C)C)oc2=O)c(Cl)c1.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.60
MEN1 O00255 5/20 0.60
TDP1 Q9NUW8 4/20 0.60
PPOX P50336 3/20 0.36
TTR P02766 1/20 0.36
NR1I2 O75469 1/20 0.36
PNLIP P16233 6/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
MAPT P10636 3/20 0.35
MAPK1 P28482 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
STK39 Q9UEW8 1/20 0.34
LMNA P02545 2/20 0.34
ESRRA P11474 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7587915 0.86 TDP1 (0.58) KMT2AMEN1TDP1PPOXTTR
Dimefuron SCHEMBL7586528 0.84 KMT2A (0.52) KMT2AMEN1TDP1PPOXTTR
Oxadiazon SCHEMBL7577080 0.84 TDP1 (0.58) KMT2AMEN1TDP1PPOXTTR
Bifenox SCHEMBL7577142 0.82 TDP1 (0.55) KMT2AMEN1TDP1PPOXTTR
Oxyfluorfen SCHEMBL7578497 0.82 MEN1 (0.57) KMT2AMEN1TDP1PPOXTTR
Bifenox SCHEMBL7575338 0.81 TDP1 (0.71) KMT2AMEN1TDP1PPOXTTR
Dimefuron SCHEMBL68325 0.78 MEN1 (1.00) KMT2AMEN1TDP1PPOXNR1I2
Dimefuron SCHEMBL9138565 0.78 MEN1 (1.00) KMT2AMEN1TDP1PPOXNR1I2
Dimefuron SCHEMBL29436146 0.78 MEN1 (1.00) KMT2AMEN1TDP1PPOXNR1I2
Bifenox SCHEMBL7577683 0.78 TDP1 (0.71) KMT2AMEN1TDP1PPOXTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.