Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387996 | 0.91 | MAPT (0.45) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL7592680 | 0.83 | ALDH1A1 (0.43) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL2909396 | 0.81 | MEN1 (0.55) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL1906434 | 0.81 | ALDH1A1 (0.55) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7584127 | 0.79 | KDM4E (0.51) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL11575236 | 0.78 | MEN1 (0.52) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL7587097 | 0.75 | KDM4E (0.53) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL10386484 | 0.74 | ALDH1A1 (0.43) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL10386482 | 0.74 | MAPT (0.41) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL11575861 | 0.73 | ALDH1A1 (0.49) | MAPTMEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894831-B1 | Monoazo pigments of the quinoxaline-acetarylide type | CLARIANT GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-5910577-A | YELLOW HUE, GREATER LIGHT AND WEATHER FASTNESS | CLARIANT GMBH (DE) | 1999-06-08 | — | — | US | disclosed |
| EP-0894831-A1 | Monoazo pigments of the quinoxaline-acetarylide type | Clariant GmbH (DE) | 1999-02-03 | — | — | EP | disclosed |