SCHEMBL7586824

SCHEMBL7586824

Cn1ccc(=O)n(C(=O)O)c1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
KDM6A O15550 1/20 0.35
KDM4A O75164 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KDM5C P41229 1/20 0.35
KDM2B Q8NHM5 1/20 0.35
DOHH Q9BU89 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
CRBN Q96SW2 1/20 0.33
BRD4 O60885 1/20 0.32
TAF1 P21675 1/20 0.32
BRPF1 P55201 1/20 0.32
CREBBP Q92793 1/20 0.32
CECR2 Q9BXF3 1/20 0.32
BRD9 Q9H8M2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
CMA1 P23946 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23222667 0.67 CRBN (0.37) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL3590708 0.67 ALDH1A1 (0.43) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL5478056 0.67 KDM4E (0.35) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL8589752 0.65 BRD4 (0.34) KDM4EBRD4BRD9ALDH1A1POLB
SCHEMBL31580031 0.65 GSK3B (0.55) MAPTKMT2A
SCHEMBL21846831 0.64 CRBN (0.34) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL21911678 0.64 ALDH1A1 (0.39) KDM4ECRBNBRD4TAF1BRPF1
SCHEMBL6932284 0.62 ERN1 (0.36) KDM4ECYP2C9BRD4ALDH1A1POLB
SCHEMBL20541520 0.61 KDM4E (0.42) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL28132698 0.60 MAP2K1 (0.35) KDM2BALDH1A1POLBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000079009-A9 IMPROVED PRIMERS AND METHODS FOR THE DETECTION AND DISCRIMINATION OF NUCLEIC ACIDS INVITROGEN CORP (US) 2002-06-13 WO disclosed