SCHEMBL8589752

SCHEMBL8589752

Cc1cn(C)c(=O)n(C(=O)O)c1=O

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 8/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
BRD9 Q9H8M2 1/20 0.33
CMA1 P23946 2/20 0.32
CTSG P08311 1/20 0.32
POLB P06746 2/20 0.32
TSHR P16473 2/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PKM P14618 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16130854 0.79 P2RX4 (0.46) BRD4L3MBTL1LMNAPOLBHSD17B10
SCHEMBL6932284 0.76 ERN1 (0.36) BRD4ALDH1A1LMNAPOLBTSHR
SCHEMBL14491564 0.68 BRD4 (0.36) BRD4L3MBTL1ALDH1A1LMNABRD9
SCHEMBL19235507 0.68 BRD4 (0.36) BRD4L3MBTL1ALDH1A1LMNABRD9
SCHEMBL8544865 0.68 LMNA (0.35) BRD4ALDH1A1LMNAPOLBTSHR
SCHEMBL23029099 0.67 BRD4 (0.35) BRD4L3MBTL1ALDH1A1LMNABRD9
SCHEMBL18937487 0.67 BRD4 (0.35) BRD4L3MBTL1ALDH1A1LMNABRD9
SCHEMBL9117924 0.67 BRD4 (0.33) BRD4L3MBTL1ALDH1A1LMNAPOLB
SCHEMBL9117929 0.67 HSD17B10 (0.42) ALDH1A1LMNAPOLBTSHRHSD17B10
SCHEMBL7586824 0.65 KDM4E (0.35) BRD4ALDH1A1BRD9CMA1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639607-B1 Method and apparatus for degradation and sequencing of polymers which sequentially eliminate terminal residues PERSEPTIVE BIOSYSTEMS INC (US) 1998-01-07 EP disclosed
US-5527675-A Method for degradation and sequencing of polymers which sequentially eliminate terminal residues MILLIPORE CORPORATION (US) 1996-06-18 US disclosed
EP-0639607-A2 Method and apparatus for degradation and sequencing of polymers which sequentially eliminate terminal residues PERSEPTIVE BIOSYSTEMS, INC. (US) 1995-02-22 EP disclosed